250. PROGNOSTIC FACTORS ASSOCIATED WITH 18FDG-PET/CT IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA AFTER TRIMODALITY TREATMENT

Abstract Patients with locally advanced and potentially curable esophageal cancer (EC) should receive trimodality treatment, which involves neoadjuvant concurrent chemoradiotherapy (nCRT) followed by esophagectomy. The maximum standard uptake value (SUVmax) in SUV of 18FDG-PET/CT have been reported to be useful predicting the prognosis EC patients treated nCRT subsequent We aimed determine pathological response after therapy investigate prognostic factors associated SUVmax. This was a retrospective study squamous cell carcinoma who received esophagectomy between January 2011 December 2018 at Tri-Service General Hospital Taipei, Taiwan. Survival analysis performed using Kaplan–Meier method Cox proportional hazards model. Univariate multivariate analyses were used independent factors. A total 79 underwent esophagectomy, 50 them enrolled study. Among enrolled, 18 had pCR. post-nCRT ≥ 3 poor factor OS (hazard ratio [HR]: 3.665, P = 0.013) PFS (HR: 3.417, 0.011). Poor found pCR SUVmax ≥3 as compared those partial <3. is ESCC even